BLOOD-BRAIN BARRIER DYSFUNCTION IN AGING IS MEDIATED BY BRAIN ENDOTHELIAL SENESCENCE
Blood–brain barrier dysfunction in aging is mediated by brain endothelial senescence. Novo et al., Aging Cell. 2024;23:e14270 (2024). doi.org/10.1111/acel.14270
LIPD-LOWERING STATINS AND POLYPHENOL-BASED SUPPLEMENTATION: A SCOPING REVIEW ON DRUG-FOOD INTERACTION POTENTIAL
Lipid-lowering statins and polyphenol-based supplementation: a scoping review on drug-food interaction potential. Costa et al., Frontiers in Pharmacology 16:1541871 (2025). doi: 10.3389/fphar.2025.1541871
Adipose tissue-liver cross-talk: a route to hepatic dysfunction in pregnant women with obesity
Adipose tissue-liver cross-talk: a route to hepatic dysfunction in pregnant women with obesity. Sousa et al., Bioscience Reports 44 BSR20231679 (2024). doi: 10.1042/BSR20231679
Polyphenols: immunonutrients tipping the balance of immunometabolism in chronic diseases
Polyphenols: immunonutrients tipping the balance of immunometabolism in chronic diseases. Ferreira et al., Frontiers in Immunology 15: 1360065 (2024). doi: 10.3389/fimmu.2024.1360065
Seminar: Host-microbiome cross talk in aging, Clara Correia-Melo, Leibniz Institute of Aging, Jena, Germany. Faculty of Medicine, University of Coimbra, May 13, 2025
Spatio-temporal regulation of adult neural stem cells by microenvironment
Seminar: Spatio-temporal regulation of adult neural stem cells by microenvironment, Armen Sagathelyan, University of Otawa, Canada.
Faculty of Medicine, University of Coimbra, February 27, 2025
ERASMUS+ Blended Intensive Program on Cognitive Disorders
The University of Crete (main organizer), University of Coimbra, University of Valencia and Acibadem University organised the ERASMUS + Blended Intensive Course on Cognitive Disorders. CHAngeing partners University of Crete and University of Coimbra supported the collaboration through a quadruple helix perspective and explored the scientific links between Healthy Lifestyles supported by Mediterranean diet Culture and Brain Health.
The physical component of the course took place in Heraklion, May 5-9, 2025.
The Annual Retreat of EIT Health Ageing PhD School took place in Coimbra, December 4-7, 2023. This event enclosed close collaboration and synergies with CHAngeing partners, including students from University of Coimbra and University of Crete, and also lecturers from the University of Coimbra, FORTH and Instituto Pedro Nunes.
2 positions for PhD students at Institute of Molecular Biology and Biotechnology (FORTH)
2 positions for PhD students available at the Institute of Molecular Biology and Biotechnology, Foundation for Research and Technology-Hellas (FORTH) under the scope of CHAngeing project.
Offer Description
The research group of Neurogenetics and Ageing of IMBB under in the of the R&D project Excellence Hubs, CHAngeing - Connected Hubs in Ageing: Healthy Living to Protect Cerebrovascular Function (reference: GA: 101087071), financed by European Commission through the Horizon Europe Program, invites applications for two (2) PhD student positions.
Job Description: Investigation of genetic and dietary interventions with neuroprotective potential for healthy ageing
Qualifications: The successful applicant should hold a BSc and MSc in Biology/Biomedicine or related fields, and prior documented experience in Molecular Biology methods. The successful applicant should have been enrolled in a postgraduate program leading to a doctoral degree. The successful applicant should also have excellent scientific authoring skills and several scientific publications in peer reviewed journals in related fields and fluency in English.
Requirements
Research Field
Biological sciences
Education Level
Master Degree or equivalent
Research Field
Biological sciences
Education Level
Bachelor Degree or equivalent
Skills/Qualifications
Qualifications: The successful applicant should hold a BSc and MSc in Biology/Biomedicine or related fields, and prior documented experience in Molecular Biology methods. The successful applicant should have been enrolled in a postgraduate program leading to a doctoral degree. The successful applicant should also have excellent scientific authoring skills and several scientific publications in peer reviewed journals in related fields and fluency in English.
First year of CHAngeing project; Coimbra-Crete synergies to build next implementation activities
João Malva, coordinator of CHAngeing visited the team in FORTH and University of Crete to reinforce contacts and build synergies.
12 2023
Training Initiatives
Innovation and Entrepreneurship Forum @ EIT Health Ageing PhD School Annual Retreat
Partners form Coimbra hub (João Malva, Jorge Figueira, Sofia Viana, António Cunha) and partners from Heraklion hub (George Papamichail, Kostas Vavekis, Anastasia Giakoumaki) shared their views on challenges related with innovation and entrepreneurship training with PhD students at the EIT Health Ageing PhD School students, December 4, 2023.
MAC2023; Mitochondria in Aging, Cancer and Cell Death
Nektarios Tavernarakis gave a lecture on MAC2023, in Coimbra, December 2nd 2023.
"Mitochondrial turnover in neurodegeneration and ageing". MAC2023 and CHAngeing synergies allowed the invitation of Prof. Nektarios Tavernarakis (University of Crete and FORTH) by MAC2023 organiser and CHAngeing member Prof. Paulo Oliveira (University of Coimbra).
CHAngeing project was introduced at the City of Longevity Conference, Newcastle, July 6th 2023, as part of the roadmap of the City of Coimbra (supported by Ageing@Coimbra excellence hub) to build healthy lifestyle assessment toolkit and disseminate good practices supporting healthy lifestyles inspired by the Mediterranean Diet Culture.
The CHAngeing Entrepreneurial programme is a 4-intensive week training designed to empower
participants with the essential skills, knowledge, and connections to thrive in the fast-paced healthcare industry. This programme offers a dynamic blend of interactive workshops, expert-led mentoring sessions, and hands-on group projects, diving deep into key aspects of innovation and entrepreneurship, specifically tailored to the unique challenges and opportunities within the healthcare sector.
Key Takeaways:
• Entrepreneurship Concepts: Equip participants with the fundamentals of entrepreneurship, including needs assessment, value proposition, clinical validation, stakeholder engagement, and marketing for health startups.
• Finance and Investment Programs in Health: Gain a solid understanding of finance strategies and investment opportunities specific to healthcare ventures.
• Intellectual Property and Pitching: Learn how to manage intellectual property and develop the ability to pitch healthcare innovations to potential investors, stakeholders, and partners.
• Expert Guidance and Mentorship: Receive valuable insights from seasoned professionals in healthcare innovation, helping navigate real-world challenges.
• Multidisciplinary Collaboration: Work in diverse, multidisciplinary teams with peers from across the EU, fostering cross-cultural collaboration and innovative problem-solving in a real-world context.
• Networking and Partnership Building: Expand your professional network by connecting with investors, healthcare experts, and fellow innovators, identifying opportunities for collaboration and growth.
Throughout the programme, they will work in diverse, multidisciplinary teams with peers from across the EU, fostering a rich environment for cross-cultural collaboration and innovation. By the end of the course, participants will have built a solid foundation in healthcare entrepreneurship, equipping them to lead transformative innovations in the bio and health ecosystem, to succeed in a highly competitive market, and to meet the growing demands of an ageing society.
To Register in the Program please Press "Know More"
START'Ship ERASMUS+ project in synergies with CHAngeing Excellence Hubs implemented a StudentxCEO Hackathon. 16 students developed innovative solutions for business challenges raised by 5 CEOs. University of Coimbra, May 21 & 22, 2025
POPRI_International EUSAIR youth business model competition
FORTH STEP-C and Primorski Technological Park, Slovenia, co-organized the International Business Model youth competition POPRI under the scope of EUSAIR Greek Presidency 2024-2025. The vent took place in Georgioupolis, Crete, May 6-7 2025. João Malva (CHAngeing coordinator) acted as a member of the jury for University Students competition.
