International Day of the Older Person _ Coimbra 2026
UC team was at the International Day of the Older Person, in collaboration with Coimbra Municipality, offering Life Style Assessment activities. The event took place in Convento S. Francisco, October 1, 2026
09 2026
Entreview
European Researcher’s Night 2026_UC & CHUC (ULS Coimbra) teams
UC and ULS Coimbra teams participated in the European Researcher's Night, September 25, 2026, in Coimbra. Activities included Life Style Assessment with CHAngeing Life Style Assessment Toolkit.
09 2026
Outreach
European Researcher’s Night 2026_CoLab4Ageing team
The European Researcher's Night was celebrated in Coimbra, September 25. CHAngeing CoLab4Ageing team.
07 2026
Paper
CHAngeing research discoveries_Nature communication paper @ Tavernaraki’s Lab
Notably, the study uncovers a functional connection between CYLD-1 and the autophagy-lysosome system, a major cellular recycling and quality control pathway. This synergy supports neuronal homeostasis, thereby preserving cognitive and motor functions, and ultimately long-term organismal survival.
These findings reveal a new biological mechanism linking the maintenance of neural health to ageing and longevity. Understanding how deubiquitination and autophagy cooperate to maintain neuronal integrity may lead to new therapeutic strategies for neurodegenerative and other age-related diseases, with the ultimate goal of improving quality of life and promoting healthy ageing.
UC and IPN CHAngeing teams hosted Healthy Lifestyle Assessment session in Carvalhais, S. Pedro do Sul, at Festival Tradidanças August 1, 2026. This activity allowed Healthy Lifestyle Assessment with 62 citizens. Moreover, CHAngeing project was also highlighted in the round table discussion about Healthy Longevity (August 2, 2026).
Ageing is not a fatality, it should be a celebration.
In this publication, Newspaper Público, we highlight the quadruple helix-based regional consortium on Ageing, Ageing@Coimbra and Excellence Hub CHAngeing.
Newspaper "Diário de Coimbra" published a news about the Regional Meeting on Ageing and the award for best practices to support active ad healthy ageing.
The gut microbiota – the living ally between environmental and human health
We often think of ourselves as isolated individuals, but modern biology reveals a different reality: we are, in fact, walking ecosystems. Inside our digestive tract resides a vibrant community of trillions of microorganisms known as the gut microbiota.
Protecting the Brain Through the Mediterranean Diet: The Power of Fisetin
Fisetin, a flavonol present in various foods of the Mediterranean Diet, with antioxidant, anti-inflammatory, senolytic and neuroprotective properties - The power of strawberries.
This article will unveil the complex mechanisms by which food triggers the release of vital gut hormones and how the science of chrononutrition can help us synchronize our diet with our internal biological "clock" for optimal health.
The secret of the inner city:mitochondria and lysosomes
The Mediterranean Diet provides increased capacity for infrastructure maintenance. Rich in polyphenols, antioxidants, fiber, and monounsaturated fats (such as extra virgin olive oil), this diet has been linked to improving the performance of mitochondrial power plants and strengthening the lysosomal recycling system. It is a cornerstone of prevention against age-related decline.
